Effect of low-dose amitriptyline on reducing pain in clinical knee osteoarthritis compared to benztropine: study protocol of a randomised, double blind, placebo-controlled trial.

Anita E WlukaDonna M UrquhartAndrew J TeichtahlSultana Monira HussainAndrew ForbesCarolyn ArnoldYuanyuan WangFlavia M Cicuttini

Published in: BMC musculoskeletal disorders (2021)

Australian New Zealand Clinical Trials Registry prior to recruitment commencing ( ACTRN12615000301561 , March 31, 2015, amended 14 December 2018, February 2021). Additional amendment requested 18 July 2021.

Keyphrases

double blind
knee osteoarthritis
clinical trial
study protocol
placebo controlled
low dose
phase ii
sewage sludge
open label
phase iii
chronic pain
high dose
randomized controlled trial
pain management
neuropathic pain
spinal cord injury
risk assessment
spinal cord