Contemporary Understandings of Cardiovascular Disease After Cancer Radiotherapy: a Focus on Ischemic Heart Disease.
Lisa KimEmefah C LoccohReynaldo SanchezPatrick RuzUzoma AnabaTerence M WilliamsJeremy SlivnickAjay VallakatiRagavendra BaligaAhmet AyanEric D MillerDaniel AddisonPublished in: Current cardiology reports (2020)
The development of radiation-induced ischemic heart disease following radiation can lead even to early cardiotoxicities, inclusive of coronary artery disease, which limit cancer treatment outcomes. These coronary lesions tend to be diffuse, complex, and proximal. Early detection with multimodality imaging and targeted intervention is required to minimize these risks. Early awareness, detection, and management of radiation-induced cardiovascular disease are paramount as cancer survivorship continues to grow.
Keyphrases
- radiation induced
- cardiovascular disease
- papillary thyroid
- coronary artery disease
- radiation therapy
- squamous cell
- randomized controlled trial
- childhood cancer
- type diabetes
- high resolution
- cardiovascular events
- coronary artery
- early stage
- lymph node metastasis
- locally advanced
- squamous cell carcinoma
- metabolic syndrome
- young adults
- drug delivery
- photodynamic therapy
- risk assessment
- atrial fibrillation
- acute coronary syndrome
- low grade
- sensitive detection
- aortic stenosis
- rectal cancer
- ejection fraction