A systematic review and meta-analysis of the child-level effects of family-based interventions for the prevention of type 2 diabetes mellitus.
Mette KurtzhalsAnne-Louise BjerregaardJane HybschmannAlberte Laura Oest MüllertzBianca DeSilvaPeter ElsborgAnne TimmTherese Lockenwitz PetersenLau Caspar ThygesenPeter KurtzhalsTrine Flensborg-MadsenPeter BentsenLærke MygindPublished in: Obesity reviews : an official journal of the International Association for the Study of Obesity (2024)
The 4723 studies were identified, and 55 studies met the inclusion criteria. Results showed significant effects on children's body mass index (mean difference [MD], -0.18, 95% CI [-0.33 to -0.03], p = 0.02), body fat percentage (MD, -2.00, 95% CI [-3.31 to -0.69], p = 0.003), daily activity (standardized mean difference [SMD], 0.23, 95% CI [0.01; 0.44], p = 0.04), physical activity self-efficacy (SMD, 0.73, 95% CI [0.36 to 1.10], p < 0.01), intake of snacks (MD, -0.10, 95% CI [-0.17 to -0.04], p = 0.002), and sugar-sweetened beverages (SMD, -0.21, 95% CI [-0.42 to -0.01], p = 0.04). Subgroup analyses suggested that interventions aiming to change child and parent behavior simultaneously have larger effect on fasting glucose and nutrition consumption, and that interventions longer than 26 weeks have larger effects on body composition and physical activity behavior than shorter interventions.
Keyphrases
- physical activity
- body composition
- body mass index
- molecular dynamics
- mental health
- bone mineral density
- sleep quality
- young adults
- blood glucose
- resistance training
- randomized controlled trial
- clinical trial
- tyrosine kinase
- adipose tissue
- depressive symptoms
- case control
- skeletal muscle
- blood pressure
- weight loss
- double blind