Angiotensin-Converting Inhibitors and Angiotensin II Receptor Blockers and Longitudinal Change in Percent Emphysema on Computed Tomography. The Multi-Ethnic Study of Atherosclerosis Lung Study.
Megha A ParikhCarrie P AaronEric A HoffmanJoseph E SchwartzJaime MadriganoJohn H M AustinRavi KalhanGina LovasiKarol WatsonKaren Hinckley StukovskyR Graham BarrPublished in: Annals of the American Thoracic Society (2018)
In a large population-based study, ACE inhibitors and ARBs were associated with slowed progression of percent emphysema by chest CT, particularly among former smokers. Randomized clinical trials of ACE and ARB agents are warranted for the prevention and treatment of emphysema.
Keyphrases
- angiotensin ii
- angiotensin converting enzyme
- computed tomography
- chronic obstructive pulmonary disease
- vascular smooth muscle cells
- lung function
- idiopathic pulmonary fibrosis
- cardiovascular disease
- magnetic resonance imaging
- image quality
- clinical trial
- dual energy
- pulmonary fibrosis
- smoking cessation
- cystic fibrosis
- cross sectional
- double blind