Anti-inflammatory effect of diterpenes-enriched fractions from Pterodon polygalaeflorus through inhibition of macrophage migration and cytokine production.
Nathalia Regina F LealMariana Vieira ViglianoFabiana A PintoThayane V de SousaLeosvaldo S M VelozoKátia C C SabinoMaria da Graça JustoMarsen Garcia Pinto CoelhoPublished in: The Journal of pharmacy and pharmacology (2018)
The anti-inflammatory effects of Fr3 and Fr4 involve inhibition of cell migration, iNOS expression and NO production, cytokine expression (mRNA and proteins) and CD14 expression (Fr3).