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Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.

Kannan SridharanReginald P Sequeira
Published in: British journal of clinical pharmacology (2018)
The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy. Subtle differences may exist in their safety profile. The evidence is inadequate for other drugs.
Keyphrases
  • blood pressure
  • preterm birth
  • early onset
  • drug induced
  • pregnancy outcomes
  • clinical trial
  • study protocol
  • phase iii
  • phase ii
  • randomized controlled trial
  • pregnant women
  • combination therapy
  • open label
  • double blind