Long non-coding RNAs TUG1 and MEG3 in patients with type 2 diabetes and their association with endoplasmic reticulum stress markers.
N HeydariR SharifiMitra NourbakhshP GolpourM NourbakhshPublished in: Journal of endocrinological investigation (2023)
The expression levels of TUG1 and MEG3 lncRNAs were increased in patients with diabetes and were associated with glycemic control and components of ER stress. Thus, these lncRNAs might be considered appropriate markers to identify ER stress due to hyperglycemia.
Keyphrases
- endoplasmic reticulum stress
- long non coding rna
- glycemic control
- poor prognosis
- induced apoptosis
- type diabetes
- blood glucose
- network analysis
- weight loss
- resting state
- genome wide identification
- insulin resistance
- genome wide analysis
- binding protein
- oxidative stress
- metabolic syndrome
- signaling pathway
- transcription factor