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Metaplastic Carcinoma of the Breast with Squamous Differentiation: A Case Report from the University Teaching Hospital of Kigali (CHUK), Rwanda.

Delphine UwamariyaCarine NyampingaAnne Yvette NsenguweraBelson Rugwizangonga
Published in: Case reports in pathology (2020)
Metaplastic breast carcinoma is a rare and aggressive condition, accounting less than 1% of breast malignancies. It presents with large mass and frequently with distant metastasis at time of diagnosis. Morphologically, it is characterized by the differentiation of neoplastic epithelium into epithelial or mesenchymal-looking elements like squamous cells, spindle cells, cartilage, or bone and has poor prognosis with its triple negative status.
Keyphrases
  • poor prognosis
  • induced apoptosis
  • cell cycle arrest
  • long non coding rna
  • high grade
  • bone marrow
  • low grade
  • lymph node
  • signaling pathway
  • cell proliferation
  • body composition