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Diagnostic Accuracy of Clinical Lymph Node Staging for Upper Tract Urothelial Cancer Patients - A Multicenter, Retrospective, Observational Study.

Maximilian PallaufDavid D'AndreaFrederik KönigEkaterina LaukthinaTakafumi YanagisawaMorgan RouprêtSiamak DaneshmandHooman DjaladatAlireza GhoreifiFrancesco SoriaKazutoshi FujitaStephen A BoorjianAaron M PotretzkeAndrea MariMathieu RoumiguiéAlessandro AntonelliAlberto BianchiZine-Eddine KheneJohn P SfakianosMarcus JamilJoost L BoormansJay D RamanNico C GrossmannAlberto BredaAxel HeidenreichFrancesco Del GiudiceNirmish SinglaSharokh F ShariatBenjamin Pradere
Published in: The Journal of urology (2022)
CCI had low sensitivity in detecting UTUC pN + disease. However, cN + increased the likelihood of pN + by almost three-fold. Thus, CCI is a rule-in but not a rule-out test. LND should remain the standard during extirpative UTUC surgery to obtain accurate N-staging. cN + could be a strong argument for early systemic treatment.
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