Sex differences in patterns of potentially inappropriate prescribing and adverse drug reactions in hospitalized older people: Findings from the SENATOR trial.

Denis O'MahonyAlfonso J Cruz-JentoftAdalsteinn GudmundssonRoy L SoizaMirko PetrovicAntonio CherubiniStephen ByrnePaula A Rochon

Published in: Journal of the American Geriatrics Society (2024)

We conclude that specific STOPP-criteria PIMs and START-criteria PPOs were identified more frequently in older women than older men during acute hospitalization, possibly contributing to higher ADR incidence in older women. Prescribers should appreciate sex differences in exposure to potentially inappropriate prescribing and ADR risk, given the preponderance of older women over older men in most clinical settings.

Keyphrases

adverse drug
middle aged
drug induced
community dwelling
electronic health record
liver failure
emergency department
physical activity
risk factors
primary care
study protocol
clinical trial
phase iii
respiratory failure
phase ii
aortic dissection
randomized controlled trial
intensive care unit
hepatitis b virus