The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis.
Hina N KhanXanthe BrandsSimona AufieroArie J HoogendijkAugustijn M KlarenbeekTjitske S R van EngelenBastiaan W HaakLonneke A van VughtJanneke HornMarcus J SchultzAeilko H ZwindermanTom van der PollBrendon P SciclunaPublished in: Critical care (London, England) (2020)
We provide a benchmark map of circRNA expression dynamics in specific immune cell subsets of sepsis patients secondary to CAP. CircRNAs were more abundant in immune cells of sepsis patients relative to healthy subjects. Further studies evaluating circRNA expression in larger cohorts of sepsis patients are warranted.