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MicroRNA-127-5p regulates matrix metalloproteinase 13 expression and interleukin-1β-induced catabolic effects in human chondrocytes.
Su Jin Park
Eun Jeong Cheon
Mi Hyun Lee
Hyun Ah Kim
Published in:
Arthritis and rheumatism (2014)
MicroRNA-127-5p is an important regulator of MMP-13 in human chondrocytes and may contribute to the development of OA.
Keyphrases
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endothelial cells
high glucose
induced pluripotent stem cells
poor prognosis
transcription factor
knee osteoarthritis
extracellular matrix
binding protein
long non coding rna
drug induced