Intensive Blood Pressure Lowering in Individuals With Low Diastolic Blood Pressure and Elevated Troponin Levels in SPRINT.

Cady Smith Jarett D Berry Rebecca Scherzer James A de Lemos Vijay Nambi Christie M Ballantyne Richard L Kravitz Anthony A Killeen Joachim H Ix Michael G Shlipak Simon B Ascher

Published in: Journal of the American Heart Association (2024)

In this nonprespecified subgroup analysis of SPRINT, individuals with low DBP and elevated hs-cTnT, low DBP and nonelevated hs-cTnT, and DBP ≥70 mm Hg derived similar cardiovascular disease and mortality benefits from intensive BP lowering. These findings warrant confirmation in other studies.

Keyphrases

blood pressure
cardiovascular disease
hypertensive patients
heart rate
type diabetes
high intensity
cardiovascular events
resistance training
clinical trial
randomized controlled trial
adipose tissue
risk factors
coronary artery disease
body composition
insulin resistance
open label
phase iii
study protocol