Loss of lower extremity muscle strength based on diabetic polyneuropathy in older patients with type 2 diabetes: Multicenter Survey of the Isometric Lower Extremity Strength in Type 2 Diabetes: Phase 2 study.
Takuo NomuraToshihiro KawaeHiroaki KataokaYukio IkedaPublished in: Journal of diabetes investigation (2020)
DPN clearly reduced LEMS in older type 2 diabetes patients within 4 years. Furthermore, DPN resulted in a loss of LEMS and decrease in mobility. Therefore, DPN development should be monitored closely, with glycemic control and LEMS kept at a high level to maintain health-related quality of life in older patients with type 2 diabetes.
Keyphrases
- type diabetes
- glycemic control
- community dwelling
- blood glucose
- middle aged
- physical activity
- end stage renal disease
- cardiovascular disease
- insulin resistance
- ejection fraction
- newly diagnosed
- weight loss
- chronic kidney disease
- cross sectional
- peritoneal dialysis
- clinical trial
- metabolic syndrome
- double blind
- skeletal muscle
- placebo controlled