Investigation of a multi-biomarker disease activity score in rheumatoid arthritis by comparison with magnetic resonance imaging, computed tomography, ultrasonography, and radiography parameters of inflammation and damage.
Simon KrabbeR BolceC H BraheU M DøhnB J EjbjergM L HetlandE H SassoD ChernoffM S HansenL S KnudsenA HansenO R MadsenM HasselquistJ MøllerM ØstergaardPublished in: Scandinavian journal of rheumatology (2016)
In this cohort, the MBDA score correlated poorly with MRI/US inflammation. However, the MBDA score and MRI/US were generally concordant in showing signs of inflammation in most patients in clinical remission during anti-tumour necrosis factor (anti-TNF) therapy. MBDA scores were elevated in all patients with structural damage progression.
Keyphrases
- disease activity
- rheumatoid arthritis
- magnetic resonance imaging
- contrast enhanced
- oxidative stress
- computed tomography
- systemic lupus erythematosus
- rheumatoid arthritis patients
- ankylosing spondylitis
- end stage renal disease
- diffusion weighted imaging
- juvenile idiopathic arthritis
- magnetic resonance
- newly diagnosed
- chronic kidney disease
- positron emission tomography
- interstitial lung disease
- prognostic factors
- ejection fraction
- stem cells
- image quality
- dual energy
- cell therapy
- patient reported
- mesenchymal stem cells