A core set of risk factors in individuals at risk of rheumatoid arthritis: a systematic literature review informing the EULAR points to consider for conducting clinical trials and observational studies in individuals at risk of rheumatoid arthritis.
Kulveer MankiaHeidi SiddleAndrea Di MatteoDeshiré Alpizar-RodriguezJoel KerryAndreas KerschbaumerDaniel AletahaPaul EmeryPublished in: RMD open (2021)
Risk factors for arthritis development in RA are specific to the at-risk population. Serum ACPA confers risk in all populations; subclinical inflammation on imaging and clinical features confer risk in at-risk individuals with MSK symptoms. This SLR informed the EULAR taskforce for points to consider on conducting clinical trials and studies in individuals at risk of RA.
Keyphrases
- rheumatoid arthritis
- clinical trial
- disease activity
- risk factors
- ankylosing spondylitis
- interstitial lung disease
- high resolution
- systemic lupus erythematosus
- oxidative stress
- randomized controlled trial
- phase ii
- mass spectrometry
- depressive symptoms
- photodynamic therapy
- idiopathic pulmonary fibrosis
- open label
- fluorescence imaging