A prospective, randomized, double-blind trial to compare body weight-adjusted and fixed doses of palonosetron for preventing postoperative nausea and vomiting in obese female patients.
Nathalia Gouveia de Araujo FerreiraIsmar Lima CavalcantiAlexandra Rezende AssadLouis BarrucandEstêvão Luiz Carvalho BragaNubia VerçosaPublished in: PloS one (2020)
A body weight-adjusted dose of palonosetron was as effective as 75 μg for preventing PONV for 48 h in obese female patients who underwent breast surgery. Hence, the fixed dose may be preferable to the body weight-adjusted dose.