Glucose uptake in pigment glia suppresses tau-induced inflammation and photoreceptor degeneration in Drosophila .

Mikiko OkaSho NakajimaEmiko Suzuki Shinya Yamamoto Kanae Ando

Published in: bioRxiv : the preprint server for biology (2024)

Tau expression in the fly retina induces glial activationPigment glial cells mediate inflammatory phenotypes in the degenerating retinaEnhanced glucose uptake in the pigment glia suppresses inflammation and photoreceptor neurodegeneration caused by tau expression.

Keyphrases

oxidative stress
poor prognosis
cerebrospinal fluid
induced apoptosis
signaling pathway
diabetic rats
blood glucose
neuropathic pain
binding protein
cell cycle arrest
high glucose
long non coding rna
type diabetes
metabolic syndrome
cell proliferation
pi k akt
optic nerve
stress induced