Cefazolin and Carbapenem Combination to Treat Persistent Methicillin-sensitive Staphylococcus aureus Bacteremia in Preterm Infants.

Stefan H F HagmannTaylor HodleMaura BrennanFrank SzczerbaIngrid Y CameloJoanna BeachyEvan R Horton

Published in: The Pediatric infectious disease journal (2023)

Encouraged by bacteremia clearance using antistaphylococcal beta-lactams plus carbapenem combination in adults with refractory methicillin-sensitive Staphylococcus aureus infection, we present our experience with 2 preterm infants and review 1 previously published case. Noted successful bacteremia clearance in all 3 must be weighed against possible adverse effects associated with carbapenem use.

Keyphrases

staphylococcus aureus
gram negative
preterm infants
multidrug resistant
acinetobacter baumannii
low birth weight
klebsiella pneumoniae
biofilm formation
methicillin resistant staphylococcus aureus
drug resistant
escherichia coli
randomized controlled trial
pseudomonas aeruginosa
systematic review