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Plant-derived oleanolic acid ameliorates markers associated with non-alcoholic fatty liver disease in a diet-induced pre-diabetes rat model.

Mlindeli GamedeLindokuhle MabuzaPhikelelani Siphosethu NgubaneAndile Khathi
Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2019)
The findings of the study suggest that OA ameliorates the risk of developing pre-diabetes-related NAFLD through the prevention of intrahepatic fat accumulation while also lowering hepatic inflammation.
Keyphrases
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • mouse model
  • oxidative stress
  • adipose tissue
  • fatty acid
  • skeletal muscle
  • insulin resistance
  • liver fibrosis