Contemporary study of multiple sclerosis disability in South East Wales.
Katharine Elizabeth HardingGillian IngramEmma Clare TallantyreFady JosephMark WardleTrevor P PickersgillMark D WillisValentina TomassiniOwen Rhys PearsonNeil P RobertsonPublished in: Journal of neurology, neurosurgery, and psychiatry (2022)
These data provide a detailed contemporary model of disability outcomes in a representative population-based MS cohort. They support a trend of increasing time to disability milestones compared with historical reference populations, and document disability variation with the use of transitional matrices. In addition, they provide essential information for patient counselling, clinical trial design, service planning and offer a comparative baseline for assessment of therapeutic interventions.
Keyphrases
- multiple sclerosis
- clinical trial
- white matter
- healthcare
- mass spectrometry
- physical activity
- type diabetes
- electronic health record
- ms ms
- study protocol
- case report
- metabolic syndrome
- smoking cessation
- cross sectional
- insulin resistance
- double blind
- social media
- skeletal muscle
- adipose tissue
- human immunodeficiency virus