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lncRNA NEAT1 Promotes Colorectal Cancer Progression by Increasing Inflammation.

Qingmin ChenYi QinMin LinZhao LiWeizhong Tang
Published in: Journal of oncology (2022)
Abnormal high expression level of NEAT1 in colorectal cancer tissues and cells leads to poor prognosis. Mechanistically, NEAT1 triggers off the proliferation and migration of colorectal cancer cells through promoting the inflammatory reaction. Clinically, the expression level of NEAT1 in serum may be a marker for diagnosis and prognosis of colorectal cancer.
Keyphrases
  • poor prognosis
  • long non coding rna
  • oxidative stress
  • induced apoptosis
  • gene expression
  • cell cycle arrest