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Anamorelin (ONO-7643) for the treatment of patients with non-small cell lung cancer and cachexia: Results from a randomized, double-blind, placebo-controlled, multicenter study of Japanese patients (ONO-7643-04).

Nobuyuki KatakamiJunji UchinoTakuma YokoyamaTateaki NaitoMasashi KondoKouzo YamadaHiromoto KitajimaKozo YoshimoriKazuhiro SatoHiroshi SaitoKeisuke AoeTetsuya TsujiYuichi TakiguchiKoichi TakayamaNaoyuki KomuraToru TakiguchiKenji Eguchi
Published in: Cancer (2017)
Anamorelin significantly increased LBM and improved anorexia symptoms and the nutritional state, but not motor function, in Japanese patients with advanced NSCLC. Because no effective treatment for cancer cachexia is currently available, anamorelin can be a beneficial treatment option. Cancer 2018;124:606-16. © 2017 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Keyphrases
  • papillary thyroid
  • squamous cell
  • double blind
  • placebo controlled
  • clinical trial
  • randomized controlled trial
  • childhood cancer
  • tyrosine kinase
  • sleep quality