Molecular Biomarkers Related to Oral Carcinoma: Clinical Trial Outcome Evaluation in a Literature Review.
Gabriele CervinoLuca FiorilloAlan Scott HerfordUmberto RomeoAlberto BianchiSalvatore CrimiCesare D'AmicoRosa De StefanoGiuseppe TroianoRossella SantoroLuigi LainoGregorio LainoMarco Cicciu'Published in: Disease markers (2019)
All the researches recorded the proteomic and genetic alterations in OC human biopsy cells. The gene modification level in the different studies, compared with samples of healthy tissues, has always been statistically significant, but it is not possible to associate publications with each other because each job is based on the measurement of different biomarkers and gene targets. Further investigations should be required in order to state scientific evidence about a clear advantage of using these biomarkers for diagnostic purpose.
Keyphrases
- clinical trial
- genome wide
- copy number
- induced apoptosis
- endothelial cells
- gene expression
- case report
- genome wide identification
- dna methylation
- randomized controlled trial
- cell cycle arrest
- ultrasound guided
- cell proliferation
- phase ii
- depressive symptoms
- induced pluripotent stem cells
- fine needle aspiration
- genome wide analysis