Sep70/Pepsin expression in hypopharynx combined with hypopharyngeal multichannel intraluminal impedance increases diagnostic sensitivity of laryngopharyngeal reflux.
Toshitaka HoppoAli H ZaidiDaisuke MatsuiSamantha A MartinYoshihiro KomatsuEmily J LloydJuliann E KosovecAlbert A CivitareseNatalie H BoydAmit ShettyAshten N OmsteadEmily SmithBlair A JobePublished in: Surgical endoscopy (2017)
The identified Sep70/Pepsin ratio may serve as a reliable biomarker for the diagnosis of LPR. As a result, this may help identify additional patients who have a false-negative HMII result due to the 24-h testing window.