Baseline Sex Differences in Pulmonary Arterial Hypertension Randomized Clinical Trials.
Corey E VentetuoloJude MoutchiaGrayson L BairdDina H ApplebyRobyn L McClellandJasleen MinhasJeff MinJohn H HolmesRyan J UrbanowiczNadine Al-NaamaniSteven M KawutPublished in: Annals of the American Thoracic Society (2022)
Sexual dimorphism in subjects enrolled in clinical trials extends to 6MWD and hemodynamics; these relationships are modified by age and BMI. Sex, age, and body size should be considered in the evaluation and interpretation of surrogate outcomes in PAH.