Galantamine is not a positive allosteric modulator of human α4β2 or α7 nicotinic acetylcholine receptors.
Natalia M KowalPhilip K AhringVivian W Y LiaoDinesh C IndurtiBenjamin S HarveySusan M O'ConnorMary ChebibElin S OlafsdottirThomas BallePublished in: British journal of pharmacology (2018)
Based on our data, we conclude that galantamine is not a positive allosteric modulator of α7 or α4β2 receptors, which represent the majority of nACh receptors in mammalian brain.