Genomic epidemiology of Escherichia coli: antimicrobial resistance through a One Health lens in sympatric humans, livestock and peri-domestic wildlife in Nairobi, Kenya.
Dishon M MuloiJames M HassellBryan A WeeMelissa J WardJudy M BettridgeVelma KivaliAlice Kiyong'aChristine NdindaNduhiu GitahiTom OukoTitus ImbomaJames AkokoMaurice K MurungiSamuel M NjorogePatrick MuindeLorren AlumasaTitus KaithoFredrick AmanyaAllan OgendoBram A D van BunnikJohn KiiruTimothy P RobinsonErastus K Kang'etheSamuel KariukiAmy B PedersenEric M FèvreMark E J WoolhousePublished in: BMC medicine (2022)
Findings of widespread carriage of AMR bacteria in human and animal populations, including in long-distance wildlife species, in community settings highlight the value of evidence-based surveillance to address antimicrobial resistance on a global scale. Our genomic analysis provided an in-depth understanding of AMR determinants at the interfaces of One Health sectors that will inform AMR prevention and control.