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Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates.

Evan C ChenHelen GandlerIsidora TošićGeoffrey G FellAshlee FioreOlga PozdnyakovaDaniel J DeAngeloIlene GalinskyMarlise R LuskinMartha S WadleighEric S WinerRebecca LeonardKelsey O'DayAdrienne de JongeDonna S NeubergA Thomas LookRichard M StoneDavid A FrankJacqueline S Garcia
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
We provide prospective, preliminary evidence that MET and FGFR are biologically active and safely targetable pathways in AML.
Keyphrases
  • acute myeloid leukemia
  • tyrosine kinase
  • allogeneic hematopoietic stem cell transplantation
  • cancer therapy
  • acute lymphoblastic leukemia
  • stem cells
  • drug delivery