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Intravenous thrombolysis with tenecteplase versus alteplase combined with endovascular treatment of anterior circulation tandem occlusions: A pooled analysis of ETIS and TETRIS.

Gaultier MarnatBertrand LapergueBenjamin GoryMaeva KyhengJulien LabreucheGuillaume TurcStephanze OlindoIgor SibonJildaz CaroffDidier SmadjaNicolas ChaussonFrederic ClarençonPierre SenersRomain BourcierRaoul PopJean-Marc OlivotMikael MazighiSolène MoulinKevin JanotChristophe CognardSonia AlamowitchGaspard Gerschenfeld
Published in: European stroke journal (2023)
In patients with tandem occlusions, IVT with tenecteplase seemed reasonably safe in particular with increased early recanalization rates. These findings remain preliminary and should be further confirmed in randomized trials.
Keyphrases
  • endovascular treatment
  • acute ischemic stroke
  • pulmonary embolism
  • high dose
  • randomized controlled trial
  • clinical trial
  • low dose