Validation of the Acute Physiology and Chronic Health Evaluation (APACHE) II and IV Score in COVID-19 Patients.

Jeroen VandenbrandeLaurens VerbruggeLiesbeth BruckersLaurien GeebelenEster GeertsIna CallebautIne GruytersLiesbeth HeremansJasperina DuboisBjorn Stessel

Published in: Critical care research and practice (2021)

APACHE IV provided the best discrimination and calibration of the considered scoring systems in critically ill COVID-19 patients, both in the overall group and in the subgroup with anti-Xa adjusted LMWH doses. Only in the subgroup analysis, discriminative abilities of APACHE IV were very good. This trial is registered with NCT04713852.

Keyphrases

phase iii
sars cov
public health
healthcare
liver failure
clinical trial
study protocol
mental health
drug induced
respiratory failure
phase ii
open label
health information
randomized controlled trial
risk assessment
aortic dissection
human health