The Drug Information Association (DIA) Europe held its 2022 annual meeting as a hybrid event, both as an in-person meeting in Brussels, Belgium, and as a virtual meeting. Many topics were discussed during this 3-day meeting, including the lessons learnt from the first 5 years' experience of the PRIME (PRIority MEdicine) scheme, the benefits and tools of the Clinical Trials Regulation, the roadmap of the electronic product information, the implementation of the substance, product, organization and referentials (SPOR) management services, and how real-world data, real-world evidence and digital health tools are changing the way clinical trials and research are performed.