PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells.

Ji Hyeon YouJaewang LeeJong-Lyel Roh

Published in: Journal of experimental & clinical cancer research : CR (2021)

PGRMC1 expression increased FAO and ferroptosis sensitivity from in vivo mice experiments. Our data suggest that PGRMC1 promotes ferroptosis by xCT inhibition in PCC.

Keyphrases

cell death
poor prognosis
electronic health record
high fat diet induced
type diabetes
skeletal muscle
deep learning