Oral β-Lactams, Fluoroquinolones, or Trimethoprim-Sulfamethoxazole for Definitive Treatment of Uncomplicated Escherichia coli or Klebsiella Species Bacteremia From a Urinary Tract Source.
Sameer AlzaidiJohn J VeilletteStephanie Shealy MayJared OlsonKatarina JacksonC Dustin WatersAllison M ButlerMary A HuttonWhitney R BuckelBrandon J WebbPublished in: Open forum infectious diseases (2023)
FQs and TMP-SMX had similar effectiveness in this real-world data set. HBBLs were associated with higher recurrence rates but suboptimal dosing may have contributed. Further studies are needed to define optimal BL dosing and duration to mitigate treatment failures.