Identification and analgesic activity study of analgesic protein Ⅶ-2 from Naja naja atra venom.

Yao SunGen-Bao ZhangShu LiXiao-Yu LiuLei ChenPeng-Ju Bao

Published in: The journal of venomous animals and toxins including tropical diseases (2024)

The analgesic mechanism of the NNAV-Ⅶ-2 protein may be associated with its binding to ASIC1a, consequently downregulating ASIC1a expression in neural tissues.

Keyphrases

neuropathic pain
anti inflammatory
binding protein
protein protein
poor prognosis
amino acid
gene expression
spinal cord injury
small molecule