Refractory and relapsed hairy-cell leukemia (HCL): Casting light on promising experimental drugs in clinical trials.

Novel drugs will soon be available to assist standard therapy for HCL and HCLv among patients with suboptimal results following PNA treatment. In particular, the BRAF inhibitors vemurafenib and dabrafenib, with or without rituximab, have revolutionized treatment of patients with relapsed or refractory disease.