Disease severity in subsequent pregnancies with RhD immunization: A nationwide cohort.
Carolien ZwiersYolentha Maria SlootwegJoke M KoelewijnPeter C LigthartJohanna van der BomInge L van KampEnrico LoprioreC Ellen Van Der SchootDick OepkesMasja De HaasPublished in: Vox sanguinis (2024)
RhD-mediated HDFN in a subsequent pregnancy is generally more severe than in the first pregnancy at risk and can be estimated using moment of antibody detection and severity in the first immunized pregnancy. Women developing antibodies in their first pregnancy of an RhD-positive child are at highest risk of severe disease in the next pregnancy.