Development of a Randomized Trial Comparing Intracranial Pressure Monitor-Based Management of Severe Pediatric Traumatic Brain Injury With Management Based on Imaging and Clinical Examination Without Intracranial Pressure Monitoring-Research Algorithms.
Randall M ChesnutNancy TemkinJames PridgeonStephen SulzbacherSilvia LujanWalter VidettaLuis Moya-BarquínKelley ChaddockRobert H BonowGustavo PetroniNahuel GuadagnoliPeter HendricksonGrimaldo Ramírez CortezNilton Yhuri CarreazoAlcides Vargas AymitumaDaniel AnchantePatrick CaquiAlberto RamírezManuel Munaico AbantoManuel Ortiz ChicchonJosé Cenzano RamosMaría Del Carmen Castro DarceRoberto Sierra MoralesPedro Brol LopezWilly MenendezSofía Posadas GutierrezVicente KevinAndrea MazariegosElie de LeonRodolfo Enrique Rodas BarriosSandra RodríguezSandra FloresOvidio AlvaradoLuis José Guzman FloresMelvin Moisa MartinezPablo GonzalezPublished in: Neurosurgery (2023)
We will study these protocols in the Benchmark Evidence from Latin America-Treatment of Raised Intracranial Pressure-Pediatrics trial in low- and middle-income countries. Second, we present them here for consideration as prototype pediatric sTBI management algorithms in the absence of published alternatives, acknowledging their limited evidentiary status. Therefore, herein, we describe our study design only, not recommended treatment protocols.