Lower plasma insulin levels during overnight closed-loop in school children with type 1 diabetes: Potential advantage? A randomized cross-over trial.
Ulrike SchierlohMalgorzata E WilinskaIneke M Pit-Ten CatePetra BaumannRoman HovorkaCarine De Beaufortnull nullPublished in: PloS one (2019)
Lower insulin doses were delivered in the closed-loop, resulting in lower plasma insulin levels, whereby glucose levels were not affected negatively. This suggests that the closed-loop administration is better targeted and hence could be more effective.