ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals.

Michelle L RatliffJoshua GartonJudith A JamesCarol F Webb

Published in: Immunity & ageing : I & A (2020)

These data suggest that ARID3a-expressing HSCs from aged individuals differ at both molecular and functional levels compared to ARID3a-expressing HSCs from young individuals.

Keyphrases

endothelial cells
induced apoptosis
poor prognosis
cell cycle arrest
copy number
genome wide
big data
induced pluripotent stem cells
cell death
oxidative stress
dna methylation
long non coding rna
artificial intelligence
genome wide analysis