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Compartment syndrome of the leg after thyroid hormone withdrawal; two cases and a systematic review of the literature.

Nicole Maria van VeelenStefan FischliFrank J P BeeresTimo EisenhutReto BabstChristoph HenzenBjörn-Christian Link
Published in: BMC endocrine disorders (2020)
Although compartment syndrome due to hypothyroidism is uncommon, it is a complication physicians should be aware of. The majority of reported cases are caused by an acute withdrawal of thyroid hormones and not by undetected hypothyroidism. No previous case of compartment syndrome caused by an iatrogenic hormone withdrawal in preparation for radioactive iodine has been published. However, as shown in this report, it may be beneficial to inform patients of this rare complication prior to hormone withdrawal in preparation for remnant ablation after thyroidectomy.
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