Impact of treatment with GLP-1RAs on suicide attempts in adults persons with type 2 diabetes: A retrospective comparative effectiveness study based on a global TriNetX health research database.

Mahmoud Nassar Anoop MisraZachary Bloomgarden

Published in: Journal of diabetes (2024)

As compared with DPP-4i, our analysis shows a protective effect associated with GLP-1RA treatment on the risk of suicide attempts among people with T2D. However, further research, particularly prospective and randomized studies, is necessary to confirm these observations and understand the underlying mechanisms.

Keyphrases

double blind
randomized controlled trial
combination therapy
study protocol
adverse drug
drug induced
data analysis