Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data.

Carla AbdelnourDaniel FerreiraMarleen van de BeekNira CedresKetil OppedalLena CavallinFrédéric BlancOlivier BousigesLars-Olof WahlundAndrea PilottoAlessandro PadovaniMercè BoadaJavier PagonabarragaJaime KulisevskyDag AarslandAfina W LemstraEric Westman

Published in: Alzheimer's research & therapy (2022)

This study demonstrates that there are subgroups of DLB patients with different biological, clinical, and demographic characteristics. These findings may have implications in the diagnosis and prognosis of DLB, as well as in the treatment response in clinical trials.

Keyphrases

clinical trial
single cell
randomized controlled trial
big data
parkinson disease
machine learning