Evaluation of Collagen Dermal Filler with Lidocaine for the Correction of Nasolabial Folds: A Randomized, Double-Blind, Multicenter Clinical Trial.

Chin-Yi YangYa-Ching Chang Hao-Chih TaiYi-Hua LiaoYu-Huei HuangRosaline Chung-Yee HuiYuan-Sung KuoShyue-Yih HorngYi-Shuan SheenTim-Mo ChenYuan-Sheng TzengChih-Hsin WangShou-Cheng TengChun-Kai Oscar ChangChang-Yi Chou

Published in: Clinical, cosmetic and investigational dermatology (2024)

The new dermal injectable collagen with lidocaine exhibited better efficacy for correcting nasolabial fold wrinkles compared to the control group. Both relieved pain and produced only transient and tolerable AEs.

Keyphrases

double blind
clinical trial
wound healing
tissue engineering
hyaluronic acid
placebo controlled
chronic pain
phase ii
phase iii
study protocol
neuropathic pain
pain management
open label
cerebral ischemia
cross sectional
spinal cord
blood brain barrier