Dynamic Molecular Markers of Otosclerosis in the Human Cochlea.
Sarah E HodgeIvan A LopezAlex CronkiteJohn HouseHirooki MatsuiGail IshiyamaAkira IshiyamaPublished in: The Annals of otology, rhinology, and laryngology (2024)
Our results propose that the activity and function of TGF-1 may play a key role in the development and pathogenesis of otosclerosis. Further studies utilizing a higher number of temporal bone specimens will be helpful for future analysis and to help decipher its role as a potential target in therapeutic interventions.