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Efficacy and safety of trifluridine/tipiracil in third-line and beyond for the treatment of patients with metastatic colorectal cancer in routine clinical practice: patterns of use and prognostic nomogram.

Ana Fernández MontesF Vazquez RiveraN Martinez LagoM Covela RúaA Cousillas CastiñeirasP Gonzalez VillarroelJ de la Cámara GómezJ C Méndez MéndezM Salgado FernándezS Candamio FolgarM Reboredo LópezM Carmona CamposE Gallardo MartínM Jorge FernándezM L Pellón AugustoL París BouzasJ García Gómez
Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2019)
The results of this study confirm the efficacy and safety of trifluridine/tipiracil in chemorefractory mCRC patients. However, patients in clinical practice differ from patients in clinical trials. Due to this, prognostic factors have special importance to offer the best therapeutic approach.
Keyphrases
  • prognostic factors
  • metastatic colorectal cancer
  • end stage renal disease
  • clinical trial
  • ejection fraction
  • chronic kidney disease
  • newly diagnosed
  • peritoneal dialysis
  • randomized controlled trial
  • patient reported