Does the addition of chemotherapy to neoadjuvant radiotherapy impact survival in high-risk extremity/trunk soft-tissue sarcoma?
Mudit ChowdharyAkansha ChowdharyNeilayan SenNicholas G ZaorskyKirtesh R PatelDian WangPublished in: Cancer (2019)
The addition of chemotherapy to neoadjuvant RT was associated with improved OS for patients with high-risk ET-STS. In the absence of randomized data evaluating CRT versus RT, these findings warrant further investigation.
Keyphrases
- locally advanced
- rectal cancer
- squamous cell carcinoma
- radiation therapy
- open label
- double blind
- electronic health record
- lymph node
- placebo controlled
- phase iii
- big data
- clinical trial
- early stage
- randomized controlled trial
- soft tissue
- phase ii
- free survival
- cardiac resynchronization therapy
- lower limb
- radiation induced
- left ventricular
- data analysis