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Cost-effectiveness of ribociclib as initial treatment for premenopausal women with advanced breast cancer in Singapore.

Lydia Pui Yee LokeSoo-Chin LeeFiona PearceMohamed Ismail Abdul AzizMohamed Ismail Abdul Aziz
Published in: Cancer reports (Hoboken, N.J.) (2020)
At its current price, adding ribociclib to endocrine therapy is unlikely to be cost-effective in Singapore for HR+, HER2- ABC. Results from this study are useful to inform future funding decisions for CDK4/6 inhibitors alongside other factors including clinical effectiveness, safety, and budget impact considerations.
Keyphrases
  • randomized controlled trial
  • systematic review
  • cell cycle
  • postmenopausal women
  • stem cells
  • breast cancer risk
  • cell proliferation
  • bone marrow
  • early breast cancer