Iron-Catalyzed Thiolation and Selenylation of Cycloalkyl Hydroperoxides via C-C Bond Cleavage.

Qing-Xin SunHe ChenShuai LiuXiao-Qiang WangXin-Hua Duan Li Na Guo

Published in: The Journal of organic chemistry (2021)

A cheap iron-catalyzed C-C bond cleavage/thiolation and selenylation of cycloalkyl hydroperoxides are presented. This redox-neutral protocol provides efficient access to diverse distal keto-functionalized thioethers and selenium compounds. Remarkably, only some amounts of disulfides are required for this transformation.

Keyphrases

room temperature
dna binding
iron deficiency
randomized controlled trial
electron transfer
minimally invasive
quantum dots
transition metal
molecularly imprinted
transcription factor
mass spectrometry
high resolution
liquid chromatography