Efficacy and safety/tolerability of pridinol: a meta-analysis of double-blind, randomized, placebo-controlled trials in adult patients with muscle pain.
Michael A ÜberallUte EssnerGerhard H H Müller-SchwefePublished in: Current medical research and opinion (2022)
The results from this meta-analysis as based on two placebo-controlled studies in adult patients with mild to moderate acute muscle pain demonstrate that a 3-week monotherapy with PRI showed a comparable safety profile, but significantly better analgesic effects and improvements of related impairments such as stiffness, tenderness, and movement restrictions compared with placebo - irrespective of its mode of administration.
Keyphrases
- placebo controlled
- double blind
- chronic pain
- neuropathic pain
- phase iii
- systematic review
- clinical trial
- phase ii
- pain management
- skeletal muscle
- phase ii study
- study protocol
- case control
- liver failure
- open label
- drug induced
- randomized controlled trial
- spinal cord
- respiratory failure
- meta analyses
- spinal cord injury
- squamous cell carcinoma
- anti inflammatory
- postoperative pain
- combination therapy
- acute respiratory distress syndrome
- locally advanced
- rectal cancer